Cellular Bioprocessing

The working group Cellular Bioprocessing develops future-oriented platforms for the collection, preparation, conservation and distribution of bioreagents and clinical samples for worldwide networks. This includes optimized processes for the production and preparation of samples and their cryopreservation. In this context, the Fraunhofer IBMT built up a global HIV cryobank of safety level S3 within the framework of the global initiative for the development of a HIV vaccine ("Collaboration for AIDS Vaccine Discovery – CAVD") which is funded by the Bill & Melinda Gates Foundation and the State Government of Saarland. The laboratory areas and the connected cryobank for bioreagents are subject to a certified quality assurance program which monitors the work according to the guidelines of "Good Clinical Laboratory Practice" (GCLP).

In addition to this, manual work sequences and cell-based assays are being automated and validated up to certification under suitable quality management systems. The production, for example, of HIV-1 pseudoviruses or infectious HIV-1 clones takes place in a fully automated system for the cultivation of eukaryotic cells, or cell-based tests such as neutralization and immune assays are being automated.

The working group Cellular Bioprocessing thus offers a platform for the further development and clinical testing of vaccines and new therapies. This biobank also serves as a cryorepository for a German-African joint project funded by the German Research Foundation (DFG) for the investigation of the pathogen Staphylococcus aureus. The scientists in Germany and Africa want to find out how widespread and resistant the pathogens are on the African continent, and what can be done to stem this deadly hazard.

Publication

International Innovation is the leading global dissemination resource
for the wider scientific, technology and research communities,dedicated
to disseminating the latest science, research and technological
innovations ona global level. More information and a complimentary
subscription offer to the publication can be found at:
www.researchmedia.eu

Offers of the Department of Bioprocessing & Bioanalytics

Equipment of the Department of Bioprocessing & Bioanalytics

Brochure of Main Department of Medical Biotechnology

Product Information Sheets of the Main Department of Medical Biotechnology

Projects of the Main Department of Medical Biotechnology

All Publications of the Main Department of Medical Bioechnology

Press Releases of the Main Department of Medical Biotechnology

Student Works in the Main Department of Medical Biotechnology