• research and development in the field of cryobiotechnology
• development of cryo specific equipment (substrates, heating/cooling boards, microscopes, etc.)
• development of freezing procedures

Biomedical Optics

• multiphoton lasermicroscopy with a femtosecond pulsed laser in the near infrared (NIR)
• optical tomography of cells and tissues
• optical diagnostic of melanoma and drug screening
• nanosurgery inside cells and tissues
• microstructuring
• nanostructering of polymers, metal films, silicon
• optical trapping
• stationary and time-resolved fluorescence spectroscopy
• fluorescence lifetime imaging (FLIM)
• Raman spectroscopy and imaging
• two-photon fluorescence correlation spectroscopy
• AFM
• electron microscopy
• vitality tests
• cell cloning assay
• ROS detection
• imaging of ECM structures (elastin, collagen)
• detection of pathogenic microorganisms
• detection of accumulation of nanoparticles in tissue
• Multiphoton-acoustic microscopy

Cryomechatronics

• research and development in the field of low-temperature electronics (digital and analog modules, sensors, RFID, optoelectronics)

• development of cryo-disposables, especially sample substrates/containers (e.g. tubes/vials and carrier plates like titer plates) with integrated electronic modules and microsystems

• development of low-temperature probing and measurement assemblies

• test and characterisation of electronic components and modules down to -196 °C

• test and characterisation of material fatigue caused by temeprature stress

• low-temperature tolerant and optimised electronic infrastructure for cryogenic sample storage tanks (based on a 32-bit microcontroller)

• design and construction of new storage technologies for the cryopreservation of biological material, e.g. novel rack-system for electronic sample and data archiving

• fabrication of mechatronic prototypes

• research and development in the field of memory-chip-based, adaptive laboratory and workflow management (»ChameleonLab«-Technology)

• development of special tools and hardware (e.g. chip reader for sample tubes and titer plates) for optimised sample handling and tracking