Simulation, Visualization & Magnetic Resonance

Fraunhofer Institute for Biomedical Engineering

Electromagnetical calculation for the design of a miniaturized electrical manipulation magnet.
© Fraunhofer IBMT.

Offers

Simulation, Visualisation & Magnetic Resonance

  • Computer aided development and test of ultrasound transducers
  • Computer aided development of test ultrasound arrays
  • sound field calculations
  • optimization of ultrasound sensors and systems
  • Computer aided development and test of gradient coils
  • Computer aided development of test gradient coil arrays
  • electromagnetical field calculations
  • Computer aided development and test of MEMS
  • calculations of flow measurements
  • coupled calculations of flow and acoustics
  • calculations of stiffness and materials properties
  • FEM based optimization of parts and devices
  • simulation of microfluidic devices and systems
  • temperature simulation
  • 3-D-construction
  • 3-D-visualization and animation in biology, chemistry, physics, medicine and engineering
  • medical image analysis and 3D-reconstruction
  • quantitative and automated evaluation of microscopic images

Group Magnetic Resonance

Biomedical Research (NMR, FT-IR)

  • evaluation of drugs by NMR spectroscopy and MR-Imaging
  • MR-microimaging and MRI (magnetic resonance tomography)
  • drug testing by NMR techniques applied to cell cultures, tumor spheroids and artificial skin (includes NMR microscopy as well)
  • studies on the effect of ointments on the human skin (in vitro and in vivo)
  • permeation behaviour of vesicles, drug-carriers and cells
  • interaction of membrane-active pharmaceuticals with model and bio-membranes
  • liposomes as carriers
  • characterization (in vitro) of cell parts and metabolic activities in cells with high-resolution solid state NMr- techniques
  • molecular characterzation of biominerialization processes
  • hydratization properties of biopolymers
  • hydratization properties of materials
  • coating of surfaces (biocompatibility)
  • in vitro and in vivo studies on the effects of ointments on skin
  • investigations on bio adhesives
  • investigations on biosensors
  • cells under extreme stress (cryoconservation, cryoprotection)
  • cell-cell and cell-surface interaction with high-resolution NMR spectroscopy
  • structure and dynamics of biofilms under flow conditions
  • image analysis with own developed software BodyScan R

Applied Polymer Research (NMR, FT-IR, AFM)

  • molecular structure and dynamics of solid polymers and biopolymers
  • diffusion behaviour of liquids in polymers
  • NMR-microimaging in composite materials
  • evaluation of filter materials (chemical industry, food industry, biotechnology, pharmacy)
  • evaluation of protection effects of waxes
  • molecular dynamics in solid polymers
  • self-organizing molecules for the production of nanostructures for technical applications

System Technology

  • non-invasive NMR flow measurements with high-resolution, fast imaging processes for the on-line control, flow behaviour on surfaces of different physica-chemical properties (biocompatibility)
  • fast 3D-MR-imaging for solid state
  • NMR probes for spectroscopy and microimaging with coil diameters of 2 to 40 mm, adapted to the objects
  • state-of-the-art gardient systems for NMR-microimaging, e.g. 200 G/cm gardient systems in x,y,z axis
  • NMR coils for medical whole-body tomographic systems (with clinical certification)
  • minimal-invasive NMR technology
  • magnetic resonance positioning systems for medical surgery
  • CAD-CAM for life and material sciences
  • consulting and studies
  • courses in NMR spectroscopy and microimaging